Bakermans-Kranenburg, Prof. M.J. (Marian)

Position:
  • Full professor
Expertise:
  • Attachment, intervention, behaviour genetics, emotion regulation, meta-analysis


Telephone number: +31 (0)71 527 3798
E-Mail: bakermans@fsw.leidenuniv.nl
Faculty / Department: Faculteit der Sociale Wetenschappen, Instituut Pedagogische Wetenschappen, Algemene en Gezinspedagogiek
Office Address: Pieter de la Court gebouw
Wassenaarseweg 52
2333 AK Leiden
Room number 4B35
Personal Homepage: www.socialsciences.leidenuniv.nl/​educationandchildstudies/​childandfamilystudies/​organisation/​bakermans-kranenburg.jsp

Academic Career

  • Professor, Centre for Child and Family Studies, Leiden University (2007-present)
  • Associate professor (UHD), Centre for Child and Family Studies and Data Theory, Leiden University (2004-2007)
  • Assistant professor (UD), Centre for Child and Family Studies and Data Theory, Leiden University (1993-2004)
  • PhD. Social Sciences, Leiden University. Title of thesis: 'Het Gehechtheidsbiografisch Interview ' (The Adult Attachment Interview: Psychometric analyses) (October 1993)
  • MA. Education, Centre for Child and Family Studies and Data Theory, Leiden University. Subject: Attachment and maternal structuring (March 1989)

Academic awards

  • Member of the KNAW ( Royal Netherlands Academy of Arts and Sciences) since 2012.
  • American Professional Society on the Abuse of Children’s Outstanding Research Article Award 2010 (with Cyr, Van IJzendoorn, and Euser)
  • NWO - VICI laureate 2009/2010.
  • Bowlby-Ainsworth Award 2005 ( New York Attachment Consortium & The Center for Mental Health Promotion). The Bowlby-Ainsworth Award recognizes founders and singular contributors to the Bowlby-Ainsworth tradition of attachment theory and research. April 2005.
  • NWO - VIDI laureate 2004. Grant for outstanding young researchers who are among the top 10-20% of their peer group
  • ISED-SCHEIDEGGER award for best PhD related paper (in Developmental Psychology, 1993)

Summary of main research interests

As part of my PhD study on the reliability and discriminant validity of the Adult Attachment Interview we invited about 90 first-time mothers to the institute. Three of them appeared to have more than one child: they had twins. Our interest had been aroused: would these twin siblings show similar attachment behaviours to their mothers (and corresponding to their mothers’ attachment representations)? The larger group of mothers was followed up in order to observe attachment behaviours of the second-born children. Results for the siblings have been reported in Van IJzendoorn et al. (2000). A study on attachment in twins was a rational next step in this line of research, and we studied the relative effects of genetic and environmental factors on infant-mother attachment (Bokhorst, Bakermans-Kranenburg, et al., 2003), infant-father attachment (Bakermans-Kranenburg, Van IJzendoorn, Bokhorst, & Schuengel, 2004), and on the association between maternal sensitivity and infant attachment security (Fearon et al., 2006). We also started the application of DNA genotyping in the context of the ongoing twin study and several other studies. Part of my job is the coordination and organization of the behavioural and molecular genetics project within the Leiden Attachment Research Program, initiated and supervised by Marinus van IJzendoorn. 

Our growing interest in the interplay between nature and nurture has led to several studies on gene-environment interaction, with a special focus on the ‘differential susceptibility’ of children to rearing influences.  Our series of molecular genetic studies on the role of Dopamine D4 Receptor gene polymorphisms did not show genetic main effects, but suggested vulnerability of children with the DRD4-7R allele to adverse environmental influences. We demonstrated increased levels of externalising behaviour problems and disorganised attachment for children with the DRD4-7R allele and environmental risk (Bakermans-Kranenburg & Van IJzendoorn, 2006; Van IJzendoorn & Bakermans-Kranenburg, 2006). However, these children were not only vulnerable to environmental risk, they also showed remarkably positive outcomes when they received supportive care. Our results suggest that the supposed vulnerability of carriers of the DRD4-7R allele is only part of the story: DRD4 may also be considered as a potential genetic marker of differential susceptibility or biological plasticity in response to environmental influences (Bakermans-Kranenburg & Van IJzendoorn, 2007). Our intervention studies provided preliminary support for this idea: toddlers with the DRD4-7R allele were more affected by experimentally induced changes in the environment than children without the allele. Using the Video-feedback Intervention to promote Positive Parenting and Sensitive Discipline (VIPP-SD, Juffer, Bakermans-Kranenburg, & Van IJzendoorn, 2008; Van Zeijl et al., 2006), we found that the intervention was particularly effective for children with the DRD4 7-R allele, both in terms of decreased externalizing behavior and in terms of lower daily cortisol levels (Bakermans-Kranenburg et al., 2008a, 2008b), a stress hormone that at this age is positively related to externalizing problem behavior (Alink et al., 2008).
At the same time we found heightened susceptibility to environmental influences of children with difficult temperaments (in non-overlapping samples): They displayed more variance in their physiological reactions to fear-inducing film clips dependent on the quality of the parent-child relationship (Gilissen et al., 2008) they showed a stronger association between parental sensitivity and decrease of early childhood externalizing problems (Van Zeijl et al., 2007), and they were more responsive to experimentally induced changes in maternal sensitivity (Klein Velderman et al., 2006).

Intervention studies as experimental manipulations of the environment have their natural place in this line of research, as has our interest in parenting. We identified a molecular genetic basis of human parenting: dopamine-related genes (DRD4, COMT) affected parents’ susceptibility to environmental stressors in relation to their parenting behaviour (Van IJzendoorn, Bakermans-Kranenburg, & Mesman, 2008). We thus extended the intriguing findings on the molecular genetics of parenting in rodents and nonhuman primates to humans. Following this line of research on the neurobiology of parenting, we now examine the underlying mechanisms of adults’ intended caregiving responses to systematically varied cry sounds, using an experimental design in an adult twin study.

Moreover, since both temperamental reactivity and dopamine-related genes emerged repeatedly as potential susceptibility factors, our aim for the future is to test whether these temperamental and genetic factors are independent, which of them shows the largest explanatory power for differential susceptibility, and how they operate perhaps in an additive or even interactive way.
     

Activities

International collaboration with  

  • Peter Fonagy -University College London, and Pascoe Fearon - University of Reading, on twin studies of attachment (see publications); and on jealousy and attachment (see publications)
  • Jay Belsky -Birkbeck University, London, on differential susceptibility and gene-environment interaction (see publications)
  • Tom Boyce -University of British Columbia, Vancouver, and Bruce Ellis -University of Arizona, Tucson, on gene-environment interaction and biological sensitivity to context (in preparation)
  • Pascoe Fearon -University of Reading, Annie Lapsley -University College London, and Glenn Roisman -University of Illinois, on the role of insecure and disorganized attachment in the development of children’s externalizing behavior (meta-analysis; see publications, and in preparation)
  • Paul Ramchandani -Oxford University, on differential susceptibility to the effects of fathers’ parenting (submitted)
  • Kristin Caspers -University of Iowa, on attachment and gene-environment interaction in adult siblings, half-siblings, and twins (see publications; submitted)
  • Alan Stein -Oxford University, Jim Elicker -Purdue University, and Rosalinda Cassibba -University of Bari, Italy, on early childhood intervention (book; see publications)
  • Howard Steele and Miriam Steele -New School for Social Research, New York, on attachment in institutionalized and adopted children (in preparation)
  • Robert McCall – University of Pittsburgh and Edward Sonuga-Barke -University of Southampton on attachment based interventions in institutionalized settings
  • Robert Bradley -University of Arkansas at Little Rock, on the assessment of the home environment (see publications)
  • Avi Sagi-Schwartz -University of Haifa, Israel, on the intergenerational transmission of attachment and trauma (meta-analyses; see publications); and on stress regulation in Holocaust survivors and their offspring; co-supervising two PhD students; one recently finished
  • Kim Bard -University of Portsmouth, on attachment in human-reared chimpanzees (see publications)
  • Yair Bar-Haim -Tel Aviv University, on attentional bias toward threat (meta-analysis, see publications)
  • David Oppenheim -University of Haifa, Israel, and Nina Koren-Karie -University of Haifa, Israel, on attachment in children with Autism Spectrum Disorders
  • Dave Pederson and Greg Moran -University of Western Ontario, on the transmission gap in disorganized attachment (see publications)
  • Chantal Cyr -University of Quebec, Montreal, on anomalous parenting behavior and on attachment in maltreated infants and toddlers (see publications)
  • Karine Verschueren -Catholic University of Leuven, Belgium, on compliance, parental sensitivity and discipline (see publications)
  • Nathan Fox -University of Maryland, Charley Zeanah -Tulane University Health Sciences Center, Charles Nelson -Harvard Medical School, and Megan Gunnar -University of Minnesota, on stress regulation in institutionalized children (in preparation)

Reviewing

  • Associate editor Attachment and Human Development.
  • Reviewer for Attachment and Human Development, Archives of General Psychiatry, Biological Psychiatry, Biological Psychology, British Journal of Developmental Psychology, Child Development, Child & Adolescent Mental Health, Developmental Psychology, Developmental Psychobiology, Early Childhood Research Quarterly, European Child & Adolescent Psychiatry, Genes, Brain and Behavior, Infant Behavior and Development, Infant & Child Development, Infant Mental Health Journal, Journal of Child Psychology and Psychiatry, Journal of Consulting and Clinical Psychology, Journal of Research in Personality, Journal of Family Psychology, Monographs of the Society for Research of Child Development, Parenting, Pediatrics, Psychological Science, Social development.
  • Reviewer of grant applications NWO (Netherlands Organization for Scientific Research), ISF (Israel Science Foundation), Scottish Executive Health Department, ZON (Zorg Onderzoek Nederland).
  • External reviewer doctoral dissertation dr. Mark Tomlinson, The University of Reading, UK (September 2004).

Selected publications

In press

  • Joosen, K. J., Mesman, J., Bakermans-Kranenburg, M.J., Pieper, S., Zeskind, P.S., & Van IJzendoorn, M.H. (in press). Physiological reactivity to infant crying and observed maternal sensitivity. Infancy
  • Naber, F.B.A., Poslawsky, I.E., van IJzendoorn, M.H., van Engeland, H., Bakermans-Kranenburg, M.J. (In press). Oxytocin enhances paternal sensitivity to a child with autism: A double-blind within-subject experiment with intranasally administered oxytocin. Journal of Autism and Developmental Disorders, 10.1007/s10803-012-1536-6
  • Tharner, A., Luijk, P.C.M., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., Jaddoe, V.W.V., Hofman, A., Verhulst, F.C., & Tiemeier, H. (in press). Infant Attachment, Parenting Stress and Child Emotional and Behavioral Problems at Age 3 Years. Parenting: Science and Practice.
  • Van IJzendoorn, M.H., Fridman, A., Bakermans-Kranenburg, M.J., & Sagi-Schwartz, A., (in press). Aftermath of genocide: Holocaust survivors’ dissociation moderates offspring level of cortisol. Journal of Trauma and Dissociation.
2012
  • Beijersbergen, M. D., Juffer, F., Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2012, February 27). Remaining or becoming secure: Parental sensitive support predicts attachment continuity from infancy to adolescence in a longitudinal adoption study. Developmental Psychology. Advance online publication. doi: 10.1037/a0027442
  • Groh, A. M., Roisman, G.I., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., & Fearon, R.M.P. (2012). The Significance of Insecure and Disorganized Attachment for Children’s Internalizing Symptoms: A Meta-Analytic Study. Child Development, 83, 591-610. doi: 10.1111/j.1467-8624.2011.01711.x.
  • Huffmeijer, R., Alink, L.R.A., Tops, M., Bakermans-Kranenburg, M.J., & Van IJzendoorn, M.J. (2012). Asymmetric frontal brain activity and parental rejection predict altruistic behavior: Moderation of oxytocin effects. Cognitive, Affective, and Behavioral Neuroscience. doi: 10.3758/s13415-011-0082-6
  • Huffmeijer, R., Alink, L.R.A., Tops, M., Grwen, K.M., Light, K.C., Bakermans-Kranenburg, M.J., & Van IJzendoorn, M.J. (2012). Salivary levels of oxytocin remain elevated for more than two hours after intranasal oxytocin administration. Neuroendocrinology Letters, 33, 21–25.
  • Jansen, P.W., Raat, H., Mackenbach, J.P., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Verhulst, F.C., Tiemeier, H. (2012). Early determinants of maternal and paternal harsh discipline. The Generation R Study. Family Relations, 61, 253-270. Doi: 10.1111/j.1741-3729.2011.00691.x.
  • Joosen, K., Mesman, J., Van IJzendoorn, M.H., & Bakermans-Kranenburg, M.J. (2012). Maternal sensitivity to infants in various settings predicts harsh discipline in toddlerhood. Attachment & Human Development, 14:2. 101-117. doi: 10.1080/14616734.2012.661217
  • Kok, R., Van IJzendoorn, M. H., Linting, M., Bakermans-Kranenburg, M. J., Tharner, A., Luijk, P. C. M., Székely, E., Jaddoe, V. W. V., Hofman, A., Verhulst, F. C., & Tiemeier, H. (2012). Attachment insecurity predicts child active resistance to parental requests in a compliance task. Child: Care, Health and Development. doi:10.1111/j.1365-2214.2012.01374.x
  • Pergamin-Hight, L., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H, & Bar-Haim,  Y. (2012). Variations in the promoter region of the serotonin-transporter gene (5HTTLPR) and biased attention for emotional information: A meta-analysis. Biological Psychiatry, 71, 373-379. doi: 10.1016/j.biopsych.2011.10.030
  • Riem, M.M.E, Van IJzendoorn, M.H., Tops, M., Boksem, M.A.S., Rombouts S.A.R.B., & Bakermans-Kranenburg, M.J. (2012). No laughing matter: Intranasal oxytocin administration changes functional brain connectivity during exposure to infant laughter. Neuropsychopharmacology, 37, 1257–1266. doi:10.1038/npp.2011.313
  • Stoltenborgh, M., Bakermans-Kranenburg, M. J., Van IJzendoorn, M. H., & Alink, L. R. A. (in press). Cultural-geographical differences in the occurrence of child physical abuse? A meta-analysis of global prevalence. International Journal of Psychology.
  • Van den Dries, L., Juffer, F., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., & Alink, L.R.A. (2012). Infants' responsiveness, attachment, and indiscriminate friendliness after international adoption from institutions or foster care in China: Application of Emotional Availability Scales to adoptive families. Development & Psychopathology, 24, 49-64. doi: 10.1017/S0954579411000654
  • Van IJzendoorn, M.H., & Bakermans-Kranenburg, M.J., (2012). A sniff of trust: meta-analysis of the effects of intranasal oxytocin administration on face recognition, trust to in-group, and trust to out-group. Psychoneuroendocrinology, 37, 438-443. doi: 10.1016/j.psyneuen.2011.07.008
2011  
  • Bakermans-Kranenburg, M.J., Dobrova-Krol, N.A., & Van IJzendoorn, M.H.(2011). Impact of institutional care on attachment disorganization and insecurity of Ukrainian preschoolers: Protective effect of the long variant of the serotonin transporter gene (5HTT). International Journal of Behavioral Development, 36, 11-18. doi: 10.1177/0165025411406858.
  • Bakermans-Kranenburg, M.J., Steele, H., Zeanah, C.H. Muhamedrahimov, R.J., Vorria, P., Dobrova-Krol, N.A., Steele, M., Van IJzendoorn, M.H., Juffer, F., & Gunnar, M.R. (2011). Attachment and emotional development in institutional care: characteristics and catch-up. Monographs of the Society for Research of Child Development , 76(4), 62-91. doi: 10.1111/j.1540-5834.2011.00628.x
  • Bakermans-Kranenburg, M.J., & Van IJzendoorn, M.H. (2011). Differential susceptibility to rearing environment depending on dopamine-related genes: New evidence and a meta-analysis. Development and Psychopathology, 23, 39-52. doi:10.1017/S0954579410000635
  • Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Caspers, K., & Philibert, R. (2011). DRD4 genotype moderates the impact of parental problems on unresolved loss or trauma. Attachment and Human Development, 13, 253-270. doi: 10.1080/14616734.2011.562415
  • Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Riem, M.M.E., Tops, M., & Alink, L.R.A. (2011). Oxytocin decreases handgrip force in reaction to infant crying in females without harsh parenting experiences. Social Cognitive and Affective Neuroscience; doi: 10.1093/scan/nsr067
  • Ellis, B.J., Boyce, W.T., Belsky, J., Bakermans-Kranenburg, M.J., & Van IJzendoorn, M.H. (2011). Differential susceptibility to the environment: a neurodevelopmental theory. Development and Psychopathology, 23, 7-28. doi:10.1017/S0954579410000611
  • Euser, E.M., Van IJzendoorn, M.H., Prinzie, P., & Bakermans-Kranenburg, M.J. (2011). Elevated child maltreatment rates in immigrant families and the role of socioeconomic differences. Child Maltreatment, 16, 63-73. doi: 10.1177/1077559510385842
  • Fridman, A., Bakermans-Kranenburg, M.J., Sagi-Schwartz, A., & Van IJzendoorn,M.H. (2011). Coping in old age with extreme childhood trauma: Aging Holocaust survivors and their offspring facing new challenges. Aging & Mental Health, 15, 232-242. doi: 10.1080/13607863.2010.505232
  • Fridman, A., Bakermans-Kranenburg, M.J., Sagi-Schwartz, A., & Van IJzendoorn, M.H. (2011). Genetic moderation of cortisol secretion in holocaust survivors: A pilot study on the role of ADRA2B. International Journal of Behavioral Development, 36, 79-84. doi: 10.1177/0165025411406859.
  • Huffmeijer, R., Tops, M., Alink, L.R.A., Bakermans-Kranenburg, M.J. & Van IJzendoorn, M.J. (2011). Love withdrawal is related to heightened processing of faces with emotional expressions and incongruent emotional feedback: Evidence from ERPs. Biological Psychology, 86, 307-313. doi: 10.1016/j.biopsycho.2011.01.003
  • Juffer, F.,  Palacios, J., LeMare, L., Sonuga-Barke, E., Tieman, W., Bakermans-Kranenburg, M.J., Vorria, P., Van IJzendoorn, M.H., & Verhulst, F. (2011). Development of adopted children with histories of early adversity. In R.B. McCall, M.H. van IJzendoorn, F. Juffer, V.K. Groza, & C.J. Groark (Eds.), Children without permanent parents: Research, practice, and policy. Monographs of the Society for Research of Child Development, 76(4), 31-61. doi: 10.1111/j.1540-5834.2011.00627.x
  • Lucassen, N., Tharner, A., Van IJzendoorn, M. H., Bakermans-Kranenburg, M. J., Volling, B. L., Verhulst, F. C., Lambregtse-Van den Berg, M. P., & Tiemeier, H. (2011, October 17). The association between paternal sensitivity and infant–father attachment security: A meta-analysis of three decades of research. Journal of Family Psychology. Advance online publication. doi: 10.1037/a0025855
  • Luijk, M.P.C.M., Roisman, G.I., Haltigan, J.D., Tiemeier, H., Booth-LaForce, C., Van IJzendoorn, M.H., Belsky, J., Uitterlinden, A.G., Jaddoe, V.W.V., Hofman, A., Verhulst, F.C., Tharner, A., & Bakermans-Kranenburg, M.J. (2011). Dopaminergic, serotonergic, and oxytonergic candidate genes associated with infant attachment security and disorganization? In search of main effects and GxE interactions. Journal of Child Psychology and Psychiatry, 52, 1295-1307. doi: 10.1111/j.1469-7610.2011.02440.x.
  • Luijk, M.P.C.M., Tharner, A., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., Jaddoe, V.W.V., Hofman, A., Verhulst, F.C., & Tiemeier, H. (2011). The association between parenting and attachment security is moderated by a polymorphism in the Mineralocorticoid Receptor gene: evidence for differential susceptibility. Biological Psychology, 88, 37-40. doi: 10.1016/j.biopsycho.2011.06.005
  • Mesman, J., Van IJzendoorn, M.H., & Bakermans-Kranenburg, M.J. (2011). Unequal in opportunity, equal in process: parental sensitivity promotes positive child development in ethnic minority families. Child Development Perspectives. doi: 10.1111/j.1750-8606.2011.00223.x
  • Out, D., Bakermans-Kranenburg, M. J., Granger, D. A., Cobbaert, C.M., & Van IJzendoorn, M.H. (2011). State and trait variance in salivary alpha-amylase: A behavioral genetic study. Biological Psychology,  88, 147-154. doi: 10.1016/j.biopsycho.2011.07.008.
  • Philibert, R., Van IJzendoorn, M.H., Caspers, K., Bakermans-Kranenburg, M.J., &  Beach, S.R.H. (2011). Low pass lymphoblast cell lines provide valid epigenetic information in methylation studies on psychiatric conditions: Reply to Aberg and Van den Oord. Biological Psychiatry, 69. doi: 10.1016/j.biopsych.2011.02.029
  • Pieper, S., Out., D., Bakermans-Kranenburg, M.J., & Van IJzendoorn, M.H. (2011).  Behavioral and molecular genetics of dissociation: The role of the serotonin transporter gene (5-HTTLPR). Journal of Traumatic Stress, 24, 373–380. doi: 10.1002/jts.20659
  • Pluess, M. Velders, F.P., Belsky, J., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., Jaddoe, V.W.V., Hofman, A., Arp, P.P., Verhulst, F.C., & Tiemeier, H. (2011). Serotonin transporter polymorphism moderates effects of prenatal maternal anxiety on infant negative emotionality. Biological Psychiatry, 69, 520-525. doi: 10.1016/j.biopsych.2010.10.006
  • Riem, M.M.E., Bakermans-Kranenburg, M.J., Pieper, S., Tops, M., Boksem, M.A.S., Vermeiren, R.R.J.M., Van IJzendoorn, M.H., Rombouts, S.A.R.B. (2011). Oxytocin modulates amygdala, insula and inferior frontal gyrus responses to infant crying: A randomized control trial. Biological Psychiatry, 70, 291-297. doi: 10.1016/j.biopsych.2011.02.006
  • Riem, M.M.E., Pieper, S., Out, D., Bakermans-Kranenburg, M.J., & Van IJzendoorn, M.H. (2011). Oxytocin receptor gene and depressive symptoms associated with physiological reactivity to infant crying. Social Cognitive and Affective Neuroscience, 6, 294-300. doi: 10.1093/scan/nsq035
  • Stoltenborgh, M., Van IJzendoorn, M. H., Euser, E. M., & Bakermans-Kranenburg, M. J. (2011). A global perspective on child sexual abuse: Meta-analysis of prevalence around the world. Child Maltreatment, 16, 79-101. doi: 10.1177/1077559511403920
  • Tharner, A.H.C.M., Luijk, P.C.M., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., Govaert, P.P., Roza, S.J., Jaddoe, V.W., Hofman, A., Verhulst, F.C., & Tiemeier, H. (2011). Subcortical structures and the neurobiology of infant attachment disorganization: a longitudinal ultrasound imaging study. Social Neuroscience. iFirst 1-12. doi: 10.1080/17470919.2010.538219
  • Tharner, A., Luijk, P.C.M., van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., Jaddoe, V.W.V., Hofman, A., Verhulst, F.C., & Tiemeier, H. (2012). Maternal lifetime history of depression and depressive symptoms in the prenatal and early postnatal period do not predict infant-mother attachment quality in a large, population-based Dutch cohort study. Attachment & Human Development, 14(1), 63-81. doi: 10.1080/14616734.2012.636659.
  • Tops M., Van IJzendoorn, M.H., Riem, M.M.E., Boksem, M.A.S., & Bakermans-Kranenburg, M.J. (2011). Oxytocin receptor gene associated with the efficiency of social auditory processing. Frontiers in Psychiatry, 2:60. doi: 10.3389/fpsyt.2011.00060
  • Van IJzendoorn, M.H., & Bakermans-Kranenburg, M.J. (2011). Differential susceptibility experiments: going beyond correlational evidence. Developmental Psychology 23, 39–52. doi:10.1017/S0954579410000635
  • Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., Belsky, J., Beach, S., Brody, G., Dodge, K.A., Greenberg, M., Posner, M., & Scott, S. (2011) Gene-by-environment experiments: A new approach to finding the missing heritability. Nature Reviews Genetics 12, 881-881, doi: 10.1038/nrg2764-c1.
  • Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., & Ebstein, R.P. (2011). Methylation Matters in Child Development: Toward Developmental Behavioral Epigenetics. Child Development Perspectives, 4, 305-310. doi: 10.1111/j.1750-8606.2011.00202.x .
  • Van IJzendoorn, M.H., Huffmeijer, R., Alink, L.R.A., Bakermans-Kranenburg, M.J. and Tops, M. (2011) The impact of oxytocin administration on charitable donating is moderated by experiences of parental love-withdrawal. Frontiers in Psychology 2:258, 1-8. doi: 10.3389/fpsyg.2011.00258
  • Van IJzendoorn, M.H., Palacios, J., Sonuga-Barke, E.J.S., Gunnar, M.R., Vorria, P., McCall, R.B., Le Mare, L., Bakermans-Kranenburg, M.J., Dobrova-Krol, N.A. & Juffer, F. (2011). Children in institutional care: Delayed development and resilience. Monographs of the Society for Research of Child Development, 76(4), 8-30. doi: 10.1111/j.1540-5834.2011.00626.x
  • Wolff, N., Noor J. Anne-Sophie E. Darlington, A.,E., Hunfeld, J.A.M., Tharner, A., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., Moll, H.A., Jaddoe, V.W.V., Hofman, A., Verhulst, F.C., Passchier, J., &  Tiemeier, H. (2011). The influence of attachment and temperament on venipuncture distress in 14-month-old infants: The Generation R Study. Infant Behavior and Development, 34:2. 293-302. doi: 10.1016/j.infbeh.2011.01.005
2010
  • Bakermans–Kranenburg, M.J. & Van IJzendoorn, M.H. (2010). Parenting matters: Family science in the genomic era. Family Science, 1, 25-35.
  • Euser, E.M., Van IJzendoorn, M.H., Prinzie, P., &  Bakermans–Kranenburg, M.J. (2010).The prevalence of child maltreatment in the Netherlands. Child Maltreatment, 15, 5-17.
  • Van den Dries, L., Juffer, F., Van IJzendoorn, M.H., & Bakermans-Kranenburg, M.J. (2010). Infants’ physical and cognitive development after international adoption from foster care or institutions in China. Journal of Developmental & Behavioral Pediatrics, 31, 144-150.
  • Van IJzendoorn, M.H. & Bakermans–Kranenburg, M.J. (2010). Stretched until it snaps:  Attachment and close relationships. Child Development Perspectives, 4, 109-111.
  • Van IJzendoorn, M.H. & Bakermans–Kranenburg, M.J. (2010). Invariance of adult attachment across gender, age, culture, and socioeconomic status? Journal of Social and Personal Relationships, 27, 200-208.
  • Van IJzendoorn, M. H., Bakermans-Kranenburg, M.J.,  Pannebakker, F., & Out, D. (2010). In defense of situational morality: Genetic, dispositional and situational determinants of children’s donating to charity. Journal of Moral Education, 39, 1-20.
  • Yaman, A., Mesman, J., Van IJzendoorn, M.H., & Bakermans-Kranenburg, M.J. (2010). Perceived family stress, parenting efficacy, and child externalizing behaviors in second-generation immigrant mothers. Social Psychiatry and Psychiatric Epidemiology, 45, 505-512.
  • Yaman, A., Mesman, J., Van IJzendoorn, M.H., & Bakermans-Kranenburg, M.J. (2010). Parenting and toddler aggression in  second-generation immigrant families: The moderating role of child temperament. Journal of Family Psychology, 24, 208-211.
  • Yaman, A., Mesman, J., Van IJzendoorn, M.H., & Bakermans-Kranenburg, M.J., & Linting, M. (2010).Parenting in an individualistic culture with a collectivistic cultural background: The case of Turkish immigrant families with toddlers in the Netherlands. Journal of Child and Family Studies, 19, 617-628.
  • Dobrova-Krol, N.A., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J. & Juffer, F. (2010). Effects of perinatal HIV infection and early institutional rearing on physical and cognitive development of children in Ukraine. Child Development, 81, 237-251.
  • Fearon, R.M.P., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Lapsley, A., & Roisman, G.I. (2010). The significance of insecure attachment and disorganization in the development of children’s externalizing behavior: A meta-analytic study. Child Development, 81, 435-456.
2009
  • Alink, L.R.A., Mesman, J., Van Zeijl, J., Stolk, M.N., Juffer, F., Koot, H.M., Bakermans-Kranenburg, M.J., & Van IJzendoorn, M.H. (2009). Maternal sensitivity moderates the relation between negative discipline and aggression in early childhood. Social Development, 18, 99-120.
  • Bakermans-Kranenburg, M.J. & Van IJzendoorn, M.H. (2009). The first 10,000 Adult Attachment Interviews:  Distributions of adult attachment representations in non-clinical and clinical groups. Attachment & Human Development, 11, 223-263.
  • Bakermans-Kranenburg, M.J., & Van IJzendoorn, M.H. (2009). No reliable gender differences in attachment across the life-span. Behavioral and Brain Sciences, 32, 22-23. Impact factor 17.5 
  • Harari, D., Bakermans-Kranenburg, M.J., De Kloet, C.S., Geuze, E., Vermetten, E., Westenberg, H.G.M., & Van IJzendoorn, M.H. (2009). Attachment representations in Dutch veterans with and without deployment-related PTSD. Attachment and Human Development 11, 515-536.
  • Juffer, F., Bakermans-Kranenburg, M.J., &Van IJzendoorn, M.H. (2009). Attachment-based interventions: heading for evidence-based ways to support families. ACAMH Occasional Papers, 29, 47-60. 
  • Kalinauskiene, L., Cekuoliene, D., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., Juffer, F., & Kusakovskaja, I. (2009). Supporting insensitive mothers: the Vilnius randomized control trial of video feedback intervention to promote maternal sensitivity and infant attachment security. Child: Care, Health & Development, 35, 613–623. 
  • Mesman, J., Van IJzendoorn, M.H., & Bakermans-Kranenburg, M.J. (2009). The many faces of the Still-Face Paradigm: A review and meta-analysis. Developmental Review, 29, 120-162. 
  • Mesman, J., Stoel, R., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Juffer, F., Koot, H.M., Alink, L.R.A. (2009). Predicting Growth Curves of Early Childhood Externalizing Problems: Differential Susceptibility of Children with Difficult Temperaments. Journal of Abnormal Child Psychology, 37, 625 – 636. 
  • Out, D., Bakermans-Kranenburg, M.J., & Van IJzendoorn, M.H. (2009). The role of disconnected and extremely insensitive parenting in the development of disorganized attachment: Validation of a new measure. Attachment & Human Development, 11, 419-443. 
  • Stolk, M.N., Mesman, J., van Zeijl, J., Alink, L.R.A., Bakermans-Kranenburg, M.J., van IJzendoorn, M.H., Juffer, F., & Koot, H.M. (2009). Early parenting intervention: family risk and first-time parenting related to intervention effectiveness. Journal of Child and Family Studies, 17, 55-83. 
  • Van den Dries, L., Juffer, F., Van IJzendoorn, M.H., & Bakermans-Kranenburg, M.J. (2009). Fostering Security? A meta-analysis of attachment in adopted children. Children and Youth Services Review, 31, 410-421. 
  • Van IJzendoorn, M.H., Bard, K.A., Bakermans-Kranenburg, M.J., & Ivan, K. (2009). Cognitive development of young nursery-reared chimpanzees in responsive versus standard care. Developmental Psychobiology, 51, 173-185. 
  • Van IJzendoorn, M.H., Euser, E.M., Prinzie, P., Juffer, F., & Bakermans–Kranenburg, M.J. (2009). Elevated risk of child maltreatment in families with stepparents but not with adoptive parents. Child Maltreatment, 14, 369-375.
2008
  • Alink, L.R.A., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., Mesman, J., Juffer, F., & Koot, H.M. (2008). Cortisol and externalizing behavior in children and adolescents: Mixed meta-analytic evidence for the inverse relation of basal cortisol and cortisol reactivity with externalizing behavior. Developmental Psychobiology, 50, 427-450.
  • Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., & Juffer (2008). Earlier is Better: A meta-analysis of 70 years of intervention improving cognitive development in institutionalized children. Monographs of the Society for Research of Child Development, 73, 279-293.
  • Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Pijlman, F.T.A., Mesman, J., & Juffer, F. (2008). Differential susceptibility to intervention: Dopamine D4 Receptor Polymorphism (DRD4 VNTR) moderates effects on toddlers’ externalizing behavior in a randomized control trial. Developmental Psychology, 44, 293-300.
  • Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Mesman, J., Alink, L.R.A., & Juffer, F. (2008). Effects of an attachment-based intervention on daily cortisol moderated by DRD4: A randomized control trial on 1-3-year-olds screened for externalizing behavior. Development & Psychopathology, 20, 805-820.
  • Bakermans-Kranenburg, M.J. & Van IJzendoorn, M.H. (2008). Oxytocin receptor (OXTR) and serotonin transporter (5-HTT) genes associated with observed parenting. Social Cognitive and Affective Neuroscience, 3, 128-134.
  • Beijersbergen, M.D., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., & Juffer, F (2008). Stress regulation in adolescents: Physiological reactivity during the Adult Attachment Interview and conflict interaction. Child Development, 79, 1707-1720.
  • Bimmel, N., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., Juffer, F., & De Geus, E.J.C. (2008). Problem behavior and heart rate reactivity in adopted adolescents: Longitudinal and concurrent relations. Journal of Research on Adolescence, 18, 201-214.
  • Dobrova-Krol, N.A., Van IJzendoorn, M. H., Bakermans-Kranenburg, M.J., Cyr, C. & Juffer, F. (2008). Physical growth delays and stress dysregulation in stunted and non-stunted Ukrainian institution-reared children. Infant Behavior and Development, 31, 539-553.
  • Gilissen, R., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H. & Van der Veer, R. (2008). Parent-child relationship, temperament, and physiological reactions to fear-inducing film clips: further evidence for differential susceptibility. Journal of Experimental Child Psychology, 99, 182-195.
  • Gilissen, R., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H. & Linting, M. (2008). Electrodermal reactivity during the Trier social stress test for children: Interaction between the serotonin transporter polymorphism and children's attachment representation. Developmental Psychobiology, 50, 615-625.
  • Mesman, J., Alink., L.R.A., Van Zeijl., J., Stolk, M.N., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Juffer, F., & Koot, H.M. (2008). The observation of early childhood physical aggression: A psychometric study of the system for coding early physical aggression (SCEPA). Aggressive Behavior, 34, 539-552.
  • Naber, F.B.A., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Dietz, C., Van Daalen, E., Swinkels, S.H.N., Buitelaar, J.K., & Van Engeland, H. (2008). Play behavior in toddlers with autism. Journal of Autism and Developmental Disorders, 38, 857-866.
  • Naber, F.B.A., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Dietz, C., Van Daalen, E., Swinkels, S.H.N., Buitelaar, J.K., & Van Engeland, H. (2008). Joint attention development in toddlers with autism. European Journal of Child and Adolescent Psychiatry, 17, 143-152.
  • Sagi-Schwartz, A., Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J. (2008) Does intergenerational transmission of trauma skip a generation? No meta-analytic evidence for tertiary traumatization with third generation of Holocaust survivors. Attachment & Human Development, 10, 105-121.
  • Stolk, M.N., Mesman, J., Van Zeijl, J., Alink, L.R.A., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Juffer, F. & Koot, H.M. (2008). Early parenting intervention aimed at maternal sensitivity and discipline: A process evaluation. Journal of Community Psychology, 36, 781-797.
  • Stolk, M.N., Mesman, J., Van Zeijl, J., Alink, L.R.A., Bakermans-Kranenburg, M.J., Van IJzendoorn, M.H., Juffer, F., and Koot, H.M. (2008). Early parenting intervention: Family risk and first-time parenting related to intervention effectiveness. Journal of Child and Family Studies, 17, 55-803.
  • Van der Hal-Van Raalte, E.A.M., Bakermans–Kranenburg. M.J., & Van IJzendoorn, M.H. (2008). Diurnal cortisol patterns and stress reactivity in child Holocaust survivors reaching old age. Aging & Mental Health, 12, 630–638.
  • Van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., & Mesman, J. (2008). Dopamine system genes associated with parenting in the context of daily hassles. Genes, Brain and Behavior, 7, 403–410.
  • Vermeer, H.J., & Bakermans-Kranenburg, M.J. (2008). Attachment to mother and nonmaternal care: bridging the gap. Attachment & Human Development, 10, 263–273.

For publications in 2007 and before please see "Published work" at the top of the page.

Teaching activities

I am involved in the bachelor course Gezinspedagogiek[Child and Family Studies], the master and research master course Attachment, state of the art, and the research master course Recent advances in Developmental Psychopathology. We discuss recent developments in the field of attachment studies, and aim at stimulating students’ knowledge and critical appreciation of newly included genetic, molecular genetic, and physiological measures in attachment research (oxytocin, alpha amylase, cortisol, heart rate variability, galvanic skin response).

Dissertations (PhD projects)

  • Stoltenborgh, M. (2012, Juni 22). It should not hurt to be a child. Prevalence of child maltreatment across the globe. Prom./coprom.: prof. dr. M.H. van IJzendoorn, prof. dr. M.J. Bakermans-Kranenburg, dr. L.R.A. Alink
  • Huffmeijer, Renske (2011, December 14). Shaping internal working models: Parental love withdrawal, oxytocin, and asymmetric frontal brain activity affect socio-emotional information processing. Prom./coprom.: prof. dr. M.H. van IJzendoorn, prof. dr. M.J. Bakermans-Kranenburg, dr. L.R.A. Alink, dr. M. Tops.
  • Tharner, A., (2011, Juni 29) Parents and Infants. Determinants of attachment in a longitudinal population-based study. Prom/coprom: Prof. dr. F.C. Verhulst, Prof. dr. M.H. van IJzendoorn, Prof. dr. M.J. Bakermans-Kranenburg, dr. H. Tiemeijer.
  • Fridman, A. (2011, maart 02) Surviving early childhood trauma: Effects of the Holocaust on suvivors' psychological and physiological well-being. Prom: Prof. dr. M.H. van IJzendoorn, Prof. dr. A. Sagi-Swartz, Prof. dr. M.J. Bakermans-Kranenburg.
  • Luijk, P.C.M. (2010, december 09) Infant attachment and stress regulation. A neurobiological study. Prom: Prof. dr. M.H. van IJzendoorn, Prof. dr. F.C. Verhulst, Prof. dr. M.H. Bakermans-Kranenburg, Dr. H. Tiemeier.
  • Mbagaya, C.V. (2010, december 01) Child maltreatment in Kenya, Zambia and The Netherlands. A cross-cultural comparison of prevalence, psychopathological sequelae, and mediation by PTSS. Prom: Prof. dr. M.H. van IJzendoorn, Prof. dr. M.J. Bakermans-Kranenburg, Prof. P.O. Oburu.
  • Kalinauskiene, L. (2010, november 12) The possibilities of intervention in mother-infant attachment relationshops. Prom: D. Cekuoliene, Prof. dr. M.H. van IJzendoorn, Prof. dr. M.J. Bakermans-Kranenburg.
  • Out, D. (2010, maart 25) Parenting unraveled. Predictors of infant attachment and responses to crying. Prof: Prof. dr. M.J. Bakermans-Kranenburg, Prof. dr. M.H. van IJzendoorn, Dr. S. Pieper.
  • Dobrova-Krol, N.A. (2009, december 09) Vulnerable children in Ukraine: Impact of institutional care and HIV on the development of preschoolers. Prom: Prof. dr. M.H. Van IJzendoorn, Prof. dr. M.J. Bakermans-Kranenburg, Prof. dr. F. Juffer.
  • Euser, E.M. (2009, november 26). Child maltreatment: Prevalence and risk factors. Prom: Prof. dr. M.H. Van IJzendoorn, Prof. dr. M.J. Bakermans-Kranenburg.
  • Barel, E. (2009, maart 05). Consequences of the holocaust for survivors: A meta-analysis. Prom.: Prof. dr. A. Sagi-Schwartz, Prof. dr. M.H. Van IJzendoorn, Prof. dr. M.J. Bakermans-Kranenburg.
  • Gilissen, R. (2008). Physiological reactivity to fear in children. Effects of temperament, attachment & the serotonin transporter gene. Prom.: Prof. dr. M.H. Van IJzendoorn, Prof. dr. M.J. Bakermans-Kranenburg & Prof. dr. R. van der Veer.
  • Beijersbergen, M.D. (2008). The Adult Attachment Interview. Coherence and validation in adolescents. Prom: Prof. dr. M.H. van IJzendoorn & Prof. dr. M.J. Bakermans-Kranenburg.
  • Pannebakker, F.D. (2007, november 01) Morality from infancy to middle childhood. Prom: Prof. dr. M.H. van IJzendoorn, Prof. dr. M.J. Bakermans-Kranenburg
  • Van der Hal-Van Raalte, E.A.M. (2007, mei 16). Early childhood Holocaust survival and the influence on well-being in later life. Prom./coprom.: Prof. dr. M.H. van IJzendoorn, Prof. dr M.J. Bakermans-Kranenburg, & Dr. D. Brom.
  • Stolk, M.N. (2007, maart 08). Parenting intervention and the caregiving environment: Cumulative risk and process evaluation. Prom./coprom.: Prof. dr. M.H. van IJzendoorn, Dr. J. Mesman, & Prof. dr. M.J. Bakermans-Kranenburg. 
  • Alink, L.R.A. (2006, november 09). Early childhood aggression. Prom./coprom.: Prof.dr F. Juffer, Prof. dr. H.M. Koot, Prof. dr. M.H. van IJzendoorn, Dr. J. Mesman, & Prof. dr. M.J. Bakermans-Kranenburg.
  • Rutgers, A.H. (2006, juni 13). Autism and attachment security.  Prom./coprom.: Prof. dr. M.H. van IJzendoorn, Prof. dr. I.A. van Berckelaer-Onnes, & Prof. dr. M.J. Bakermans-Kranenburg. 
  • Zeijl, J. van (2006, juni 07). Externalizing problems in 1-to-3-year-old children. Prom./coprom.: Prof. dr. M.H. van IJzendoorn, Prof.dr. F. Juffer, Prof. dr. M.J. Bakermans-Kranenburg, & Dr. J. Mesman.
  • Klein Velderman, M. (2005, november 24). The Leiden VIPP and VIPP-R study. Evaluation of a short-term preventive attachment-based intervention in infancy. Prom./coprom.: Prof. dr. M.H. van IJzendoorn, Prof. dr. M.J. Bakermans-Kranenburg, & Prof.dr. F. Juffer.
  • Jaffari-Bimmel, N. (2005, oktober 24). Development and adjustment of adopted adolescents: Longitudinal and concurrent factors. Prom./coprom.: Prof. dr. F. Juffer, Prof. dr. M.H. van IJzendoorn, & Prof. dr. M.J. Bakermans-Kranenburg. 
  • Caroline L. Bokhorst (2004, mei 27). Attachment in twins.
  • Ingrid L. van der Mark (2001, september 12). The development of empathy and compliance in toddlers: The role of parenting, attachment, and temperament. 
  • Carlo Schuengel (1996, november 06). Attachment, loss, and maternal behavior : a study on intergenerational transmission . Prom./coprom.: Prof. dr. M.H. van IJzendoorn, Prof. dr. M.J. Bakermans-Kranenburg.

Web editor Child and Family Studies
Last Modified: 10-05-2012