The central aim of the research programme is the search for determinants and risk- or protective factors for neurodevelopmental problems in adaptive behaviour. The detection of determinants, risk factors and protective factors of developmental problems during childhood is relevant for prevention, intervention, treatment and optimal coping.

Dysfunctional brain-behaviour interactions may lead to developmental psychopathology and result in social dysfunctioning (social inadequacy or aggression) and cognitive and emotional problems. Serious developmental problems can lead to very serious outcome, like psychosis, or other chronic problems that account for a lifetime of intensive use of care.