Prof. Sander Nieuwenhuis, PhD

Telephone number: +31 (0)71 527 3834
Faculty / Department: Faculteit der Sociale Wetenschappen, Instituut Psychologie, Cognitieve Psychologie
Office Address: Pieter de la Court gebouw
Wassenaarseweg 52
2333 AK Leiden
Room number 2B13
Personal Homepage:

Sander Nieuwenhuis is interested in how the brain regulates and monitors information processing to optimize behavioral performance. His primary focus is on the functions of the prefrontal cortex and the noradrenergic system. In his research he uses EEG, fMRI, psychofarmacology, computational models, and various behavioral methods. For more information, see the Curriculum vitae at the personal webpage Sander Nieuwenhuis.


  • Yeung, N., Bogacz, R., Holroyd, C.B., Nieuwenhuis, S., & Cohen, J.D. (in press). Theta phase-resetting and the error-related negativity. Psychophysiology.
  • Nieuwenhuis, S., Schweizer, T.S., Mars, R.B., Botvinick, M.M., & Hajcak, G. (in press). Error-likelihood prediction in the medial frontal cortex: A critical evaluation. Cerebral Cortex.
  • Hajcak, G., & Nieuwenhuis, S. (in press). Reappraisal modulates the electrocortical response to unpleasant pictures. Cognitive, Affective & Behavioral Neuroscience.
  • Nieuwenhuis, S., Stins, J.F., Posthuma, D., Polderman, T.J.C., Boomsma, D.I., & De Geus, E.J. (in press). Accounting for sequential trial effects in the flanker task: Conflict adaptation or associative priming? Memory & Cognition.
  • Olivers, C.N.L., & Nieuwenhuis, S. (2006). The beneficial effects of additional task load, positive affect, and instruction on the attentional blink. Journal of Experimental Psychology: Human Perception and Performance, 32, 364-379.
  • Donkers, F.C.L., Nieuwenhuis, S., & Van Boxtel, G.J.M. (2005). Mediofrontal negativities to averted gains and losses in the absence of responding. Cognitive Brain Research, 25, 777-787.
  • Nieuwenhuis, S., & Yeung, N. (2005). Neural mechanisms of attention and control: Losing our inhibitions? Nature Neuroscience, 8, 1631-1633.
  • Overbeek, T.J.M., Nieuwenhuis, S., & Ridderinkhof, K.R. (2005). Dissociable components of error processing: On the functional significance of the PE vis-àvis the ERN/NE . Journal of Psychophysiology, 19, 319-329.
  • Mars, R.B., Coles, M.G.H., Grol, M.J., Holroyd, C.B., Nieuwenhuis, S., Hulstijn, W., & Toni, I. (2005). Neural dynamics of error processing in medial frontal cortex. NeuroImage, 28, 1007-1013.
  • Talsma, D., Slagter, H.A., Nieuwenhuis, S., Hage, J., & Kok, A. (2005). The orienting of visuospatial attention: An event-related brain potential study. Cognitive Brain Research, 25, 117-129.
  • Hajcak, G., Nieuwenhuis, S., Ridderinkhof, K.R., & Simons, R.F. (2005). Error-preceding brain activity: Robustness, temporal dynamics, and boundary conditions. Biological Psychology, 70, 67-78.
  • Nieuwenhuis, S., Gilzenrat, M.S., Holmes, B.D., & Cohen, J.D. (2005). The role of the locus coeruleus in mediating the attentional blink: A neurocomputational theory. Journal of Experimental Psychology: General, 134, 291-307.
  • Nieuwenhuis, S., Aston-Jones, G., & Cohen, J.D. (2005). Decision making, the P3, and the locus coeruleus-norepinephrine system. Psychological Bulletin, 131, 510-532.
  • Nieuwenhuis, S., Slagter, H., Alting von Geusau, N., Heslenfeld, D.J., & Holroyd, C.B. (2005). Knowing good from bad: Differential activation of human cortical areas by positive and negative outcomes. European Journal of Neuroscience, 21, 3161-3168.
  • Nieuwenhuis, S. * , Nielen, M. * , Mol, N., Hajcak, G., & Veltman, D. (2005). Performance monitoring in obsessive-compulsive disorder. Psychiatry Research, 134, 111-122. (* = shared first authors)
  • Nieuwenhuis, S., Heslenfeld, D.J., Alting von Geusau, N.J., Mars, R.B., Holroyd, C.B., & Yeung, N. (2005). Activity in human reward-sensitive brain areas is strongly context dependent. NeuroImage, 25, 1302-1309.
  • Olivers, C.N.L., & Nieuwenhuis, S. (2005). The beneficial effect of concurrent task-irrelevant mental activity on temporal attention. Psychological Science, 16, 265-269.
  • Nieuwenhuis, S., Broerse, A., Nielen, M.M.A., & De Jong, R. (2004). A goal activation approach to the study of executive function: An application to antisaccade tasks. Brain and Cognition, 56, 198-214.
  • Ridderinkhof, K.R., Ullsperger, M., Crone, E.A., & Nieuwenhuis, S. (2004). The role of medial frontal cortex in cognitive control. Science, 306, 443-447.
  • Nieuwenhuis, S., Holroyd C.B., Mol, N., & Coles, M.G.H. (2004). Reinforcement-related brain potentials from medial frontal cortex: Origins and functional significance. Neuroscience & Biobehavioral Reviews, 28, 441-448.
  • Holroyd, C.B., Nieuwenhuis, S., Mars, R.B., & Coles, M.G.H. (2004). Anterior cingulate cortex, selection for action, and error processing. In: Cognitive Neuroscience of Attention (ed. M.I. Posner), pp. 219-231. New York: Guilford Press.
  • Nieuwenhuis, S., Yeung, N., Holroyd, C.B., Schurger, A., & Cohen, J.D. (2004). Sensitivity of electrophysiological activity from medial frontal cortex to utilitarian and performance feedback. Cerebral Cortex, 14, 741-747.
  • Holroyd C.B. * , Nieuwenhuis, S. * , Yeung, N., Nystrom, L.E., Mars, R.B., Coles, M.G.H., & Cohen, J.D. (2004). Dorsal anterior cingulate cortex shows fMRI response to internal and external error signals. Nature Neuroscience, 7, 497-498. (* = shared first authors)
  • Van der Veen, F.M., Nieuwenhuis, S., Crone, E.A., & Van der Molen, M.W. (2004). Cardiac and electro-cortical responses to performance feedback reflect different aspects of feedback processing. In: Errors, Conflicts and the Brain.Current Opinions on Performance Monitoring (eds. M. Ullsperger & M. Falkenstein), pp. 63-70. Leipzig: MPI of Cognitive Neuroscience.
  • Nieuwenhuis, S., Yeung, N., & Cohen, J.D. (2004). Stimulus modality, perceptual overlap, and the Go/NoGo N2. Psychophysiology, 41, 157-160.
  • Holroyd, C.B., Nieuwenhuis, S., Yeung, N., & Cohen, J.D. (2003). Errors in reward prediction are reflected in the event-related brain potential. Neuroreport, 14, 2481-2484.
  • Ridderinkhof, K.R., Nieuwenhuis, S., & Bashore, T.R. (2003). Errors are foreshadowed in brain potentials associated with action monitoring in cingulate cortex. Neuroscience Letters, 348, 1-4.
  • Nieuwenhuis, S., Yeung, N., Van den Wildenberg, W. & Ridderinkhof, K.R. (2003). Electrophysiological correlates of anterior cingulate function in a Go/NoGo task: Effects of response conflict and trial-type frequency. Cognitive, Affective & Behavioral Neuroscience, 3, 17-26.
  • Nieuwenhuis, S., Yeung, N., & Cohen, J.D. (2003). A computational simulation of electrophysiological markers of anterior cingulate activity in a Go/NoGo task. Technical Report 2003/1, Center for the Study of Brain, Mind, and Behavior, Princeton University.
  • Holroyd, C.B., Coles, M.G.H., & Nieuwenhuis, S. (2002). Medial prefrontal cortex and error potentials. Science, 296, 1610-1611.
  • Nieuwenhuis, S., Ridderinkhof, K.R., Talsma, D., Coles, M.G.H., Holroyd, C.B., Kok, A., & Van der Molen (2002). A computational account of altered error processing in older age: Dopamine and the error-related negativity. Cognitive, Affective & Behavioral Neuroscience, 2, 19-36.
  • Nieuwenhuis, S., & Monsell, S. (2002). Residual costs in task-switching: Testing the failure-to-engage hypothesis. Psychonomic Bulletin & Review, 9, 86-92.
  • Nieuwenhuis, S., Ridderinkhof, K.R., Blom, J., Band, G.P.H., & Kok (2001). Error-related brain potentials are differentially related to awareness of response errors: Evidence from an antisaccade task. Psychophysiology, 38, 752-760.
  • Nieuwenhuis, S., Ridderinkhof, K.R., De Jong, R., Kok, A., & Van der Molen, M.W. (2000). Inhibitory inefficiency and failures of intention activation: Agerelated decline in the control of saccadic eye movements. Psychology and Aging, 15, 635–647.
  • Lorist, M..M., Klein, M., Nieuwenhuis, S., De Jong, R., Mulder, G., & Meijman, T.F. (2000). Mental fatigue and task control: Planning and preparation. Psychophysiology, 37, 614-625.

Dutch publications:

  • Wagenmakers, E.J., & Nieuwenhuis, S. (2005). Damasio’s error? De somatic marker hypothese onder vuur. Neuropraxis, nr. 6, 165-169.
  • Nieuwenhuis, S. (2005). Foutendetectie in de menselijke hersenen. Neuropraxis, nr. 3, 59-63.
  • Nieuwenhuis, S. & Olsthoorn, N. (1999). Stamboom van de Nederlandse Psychonomie (poster).

Last Modified: 24-12-2015